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74124-79-1 - N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide - Su2O - H26629 - Alfa Aesar

H26629 N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide

CAS-Nummer
74124-79-1
Synonyme
Su2O

Größe Preis ($) Menge Verfügbarkeit
1g 30,70
5g 87,50
25g 294,00
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N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide

MDL
MFCD00009767
EINECS
277-730-3

Chemische Eigenschaften

Formel
C9H8N2O7
Molmasse
256.17
Schmelzpunkt
190° dec.
Löslichkeit
Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.

Anwendungen

N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Bemerkungen

Moisture sensitive. Store in a cool place. Incompatible with strong acids and oxidizing agents.

Literaturverweise

Černoch, P.; Černochová, Z.; Kučka, J.; Hrubý, M.; Petrova, S.; Št?pánek, P. Thermoresponsive polymer system based on poly(N-vinylcaprolactam) intended for local radiotherapy applications. Appl. Radiat. Isot. 2015, 98, 7-12.

Nale, D. B.; Bhanage, B. M. Copper-catalyzed efficient synthesis of a 2-benzimidazolone scaffold from 2-nitroaniline and dimethyl carbonate via a hydrosilylation reaction. Green Chem. 2015, 17 (4), 2480-2486.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
1499137
Harmonized Tariff Code
2925.19
TSCA
No

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