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As pharmaceutical intermediate. As a metabolite of Capsaicin.
Tamara Meiresonne,; Guido Verniest,; Norbert De Kimpe,; Sven Mangelinckx. Synthesis of 2-Fluoro-1,4-benzoxazines and 2-Fluoro-1,4-benzoxazepin-5-ones by Exploring the Nucleophilic Vinylic Substitution (SNV) Reaction of gem-Difluoroenamides. J. Org. Chem. 2015 , 80 (10) ,5111-5124.
Joseph T. Repinea,; Douglas S. Johnsona,; Timothy Stuka,; Andrew D. Whitea,; Michael A. Stiera,; Tingsheng Lib,; Zhixiang Yangb,; Samarendra N. Maiti. Synthesis of fluorinated 1,8-naphthyridinone derivatives. Tetrahedron Letters. 2007, 48 46,8189-8191.
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: