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4395-98-6 - 4-Cyanopiperidine, 96% - Piperidine-4-carbonitrile - H27722 - Alfa Aesar

H27722 4-Cyanopiperidine, 96%

CAS-Nummer
4395-98-6
Synonyme
Piperidine-4-carbonitrile

Größe Preis ($) Menge Verfügbarkeit
5g 63,99
25g 169,60
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4-Cyanopiperidine, 96%

MDL
MFCD05022468

Chemische Eigenschaften

Formel
C6H10N2
Molmasse
110.16
Siedepunkt
226°
Flammpunkt
91°(196°F)
Dichte
0.98
Brechungsindex
1.4755
Löslichkeit
Soluble in chloroform.

Anwendungen

4-Cyanopiperidine is used as an intermediate for the preparation of pharmaceutical substances like antidepressants and anti-inflammatory. It is used as a precursor for the synthesis of piperidine derivatives.

Bemerkungen

Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Literaturverweise

Tran, L. D.; Roane, J.; Daugulis, O. Directed Amination of Non-Acidic Arene C[BOND]H Bonds by a Copper-Silver Catalytic System. Angew. Chem. Int. Ed. 2013, 52 (23), 6043-6046.

Woo, H. M.; Lee, Y. S.; Roh, E. J.; Seo, S. H.; Song, C. M.; Chung, H. J.; Pae, A. N.; Shin, K. J. Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers. Bioorg. Med. Chem. Lett. 2011, 21 (19), 5910-5915.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H311-H302-H332-H315-H319-H335-H227

Toxic in contact with skin. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Sicherheitshinweise: P280h-P305+P351+P338-P309-P310

Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.

Weitere Referenzen

Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2933.39
TSCA
No

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