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1,1'-Thiocarbonyldi-2(1H)-pyridone is used in the preparation of thio-analogs of thioureas, sulforaphane and 2-furan-2-yl-3-hydroxy-6-isothiocyanato-chromen-4-one. It is involved in the preparation of norbiotinamine and its reactive derivatives such as isothiocyanates.
Kumar, S.; Spano, M. N.; Arya, D. P. Influence of linker length in shape recognition of B? DNA by dimeric aminoglycosides. Bioorg. Med. Chem. 2015, 23 (13), 3105-3109.
Kim, M. S.; Ki, Y.; Ahn, S. Y.; Yoon, S.; Kim, S. E.; Park, H. G.; Sun, W.; Son, K.; Cui, M.; Choi, S.; Pearce, L. V.; Esch, T. E.; DeAndrea-Lazarus, I. A.; Blumberg, P. M.; Pearce, L. V. Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands. Bioorg. Med. Chem. Lett. 2014, 24 (1), 382-385.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.