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5334-39-4 - 3-Methyl-4-nitro-1H-pyrazole, 97% - H30860 - Alfa Aesar

H30860 3-Methyl-4-nitro-1H-pyrazole, 97%

CAS-Nummer
5334-39-4
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 73,13
25g 243,08
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3-Methyl-4-nitro-1H-pyrazole, 97%

MDL
MFCD00037864

Chemische Eigenschaften

Formel
C4H5N3O2
Molmasse
127.10
Schmelzpunkt
131-134°
Siedepunkt
325°
Löslichkeit
Slightly soluble in water.

Anwendungen

3-Methyl-4-nitropyrazole is a reactant used in the preparation of aminopyrazole derivatives as potent, selective and brain penetrant Leucine-rich repeat kinase 2(LRRK2) small molecule inhibitors.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literaturverweise

Estrada, A.A., et. al. Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors. J. Med. Chem,2014, 57(3), 921-936.

K Chang, MR Grimmett; DD Ward; and RT Weavers. The Nitration of Brominated Pyrazoles in Aqueous Sulfuric Acid. Australian Journal of Chemistry,1979, 32 (8), 1727 - 1734.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2933.19
TSCA
No
RTECS
UQ7435000

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