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4-Fluoro-3-(trifluoromethyl)aniline is used in the synthesis of trifluoromethylated poly(phenylene oxide). It is used in the preparation of 2-[3-(4-fluoro-3-trifluoromethyl-phenyl)-ureido]-2-methyl-propionic acid methyl ester by reacting with 2-isocyanato-2-methyl-propionic acid methyl ester. It is also used as a chemical intermediate in the synthesis of agrochemicals, pharmaceuticals and dyes.
Abbott, P. A.; Bonnert, R. V.; Caffrey, M. V.; Cage, P. A.; Cooke, A. J.; Donald, D. K.; Furber, M.; Hill, S.; Withnall, J. Fused mesoionic heterocycles: synthesis of [1,2,3]triazolo[1,5-a]quinoline, [1,2,3]triazolo[1,5-a]quinazoline, [1,2,3]triazolo[1,5-a]quinoxaline and [1,2,3]triazolo[5,1-c]benzotriazine derivatives. Tetrahedron 2002, 58 (16), 3185-3198.
Gefahrenhinweise (EU): H302-H311-H332-H315-H319
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.