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150020-64-7 - 6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97% - H33683 - Alfa Aesar

H33683 6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%

CAS-Nummer
150020-64-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 81,40
5g 272,00
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6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%

MDL
MFCD00205139

Chemische Eigenschaften

Formel
C5H2Cl2N2O2S2
Molmasse
257.12
Schmelzpunkt
138-140°
Sensitivität
Moisture Sensitive
Löslichkeit
Sparingly soluble in water.(0.26 g/L) (25°C),

Anwendungen

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Bemerkungen

Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.

Literaturverweise

C. Elisabet Tranberg.; Andrea Zickgraf.; Brian N. Giunta.; Henning Luetjens.; Heidi Figler.; Lauren J. Murphree.; Ruediger Falke.; Holger Fleischer.; ? Joel Linden.; Peter J. Scammells.; Ray. A. Olsson. 2-Amino-3-aroyl-4,5-alkylthiophenes:? Agonist Allosteric Enhancers at Human A1 Adenosine Receptors.J. Med. Chem. 2002, 45 (2),382-389 .

Robert H. Dodd.; Catherine Ouannes.; Malka Robert-Gero.; Pierre Potier. Hybrid molecules: growth inhibition of Leishmania donovani promastigotes by thiosemicarbazones of 3-carboxy-.beta.-carbolines.J. Med. Chem. 1989, 32 (6),1272-1276 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
8
Verpackungsgruppe
III
Harmonized Tariff Code
2934.99
TSCA
No

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