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Ethyl 2-amino-5-phenylthiophene-3-carboxylate is used as a pharmaceutical intermediate.
Dan-Dan Zhao; Li Li; Fan Xu; Qi Wu; Xian-Fu Lin. Bovine serum albumin-catalyzed one-pot synthesis of 2-aminothiophenes via Gewald reaction. Journal of Molecular Catalysis B: Enzymatic. 2013, 95 29-35.
Yijun Huang; Siglinde Wolf; Michal Bista; Lidio Meireles; Carlos Camacho; Tad A. Holak and Alexander Dömling. 1,4-Thienodiazepine-2,5-diones via MCR (I): Synthesis, Virtual Space and p53-Mdm2 Activity. Chemical Biology & Drug Design. 2010, 76 (2), 116-129.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.