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2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) may be used in the synthesis of 6-methyl-2-thiophenoxynicotinic acid, required for the preparation of europium complex for staining the nucleolus of NIH 3T3, HeLa and HDF cells.
Xavier Just-Baringo,; Fernando Albericio,; Mercedes Álvarez. From 2,6-Dichloronicotinic Acid to Thiopeptide Cores. European Journal of Organic Chemistry. 2013, 2013 (28) , 6404-6419.
Xavier Just-Baringo,; Dr. Paolo Bruno,; Dr. Lars K. Ottesen,; Dr. Librada M. Cañedo,; Prof. Fernando Albericio,; Prof. Mercedes Álvare. Total Synthesis and Stereochemical Assignment of Baringolin. Angewandte Chemie. 2013, 125 (30),7972-7975.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.