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6-Trifluoromethyl-3-pyridinesulfonyl Chloride is a chemical used for the preparation of N-sulfonamido polycyclic pyrazolyl compounds for treatment of cognitive disorders.
Richard J. Cremlyn,; Graham P. Jones,; Fred J. Swinbourne,; Kin Yung.Some Reactions Of Pyridine-3-Sulfonyl Chloride. Phosphorus and Sulfur and the Related Elements. 1980, 8(2), 189-195.
Danielle L. Aubele,; Anh P. Truong,; Darren B. Dressen,; Gary D. Probst,; Simeon Bowers,; Matthew N. Mattson,; Chris M. Semko,; Minghua Sun,; Albert W. Garofalo,; Andrei W. Konradi,; Hing L. Sham,; Wes Zmolek,; Karina Wong,; Erich Goldbach,; Kevin P. Quinn,; John-Michael Sauer.Design, synthesis and structure-activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent γ-secretase inhibitors . Bioorganic & Medicinal Chemistry Letters. 2011, 21(19), 5791-5794.
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.