2-Cyanobenzoic acid has been used as reactant in the synthesis of T-box riboswitch antiterminator RNA-binding oxazolidinone derivatives, Benzoate modified β-cyclodextrin derivatives and Pyrrolo[1,2-f]triazines for use as JAK2 inhibitors. As a reactant involved in decarboxylation, decarboxylative halogenation and protodecarboxylation.
Anlai Wang; John A.Maguire; Ed Biehl. Preparation of 2-cyanobenzoic acids from the reaction of bromobenzoic acids with arylacetonitriles and LDA. J. Org. Chem. 1998, 63, (8),2451-2455
Dacio Adhemar Iglesias; Danila Lujan Ruiz; Patricia Ercilia Allegretti. Experimental study of tautomeric equilibria of 2-cyanobenzoic acids in gas, solution and solid phase. Journal of Applied Solution Chemistry and Modeling. 2012, 1, 113-120
Gefahrenhinweise (EU): H302-H312-H332-H315-H319-H335
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.