It can be heated to produce 2-trifluoromethyl-3H-quinazoline-4-thione in the presence of reagent molecular sieves and solvent CHCl3 with reaction time of 2 hours. It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields.
Chia-Yang Shiau, et al. Reactions of 2-aminothiobenzamide with isocyanates: a new synthesis of 2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one and 3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-6(7H)-one. J. Heterocycl. Chem.,1989,26(3), 595-596.
R. Morrin Acheson, et al. Synthesis and X-ray crystal structures of 2,3-dihydro-2-mercapto-2,1,3-benzophosphadiazine-4(1H)-thione 2-sulphide derivatives.J. Chem. Soc., Perkin Trans. 2,1985,(12), 1913-1917.
Gefahrenhinweise (EU): H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.