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51805-45-9 - Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water - TCEP HCl - H51864 - Alfa Aesar

H51864 Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

CAS-Nummer
51805-45-9
Synonyme
TCEP HCl

Größe Preis ($) Menge Verfügbarkeit
5ml 39,00
25ml 159,00
100ml 515,00
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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

MDL
MFCD00145469

Chemische Eigenschaften

Formel
C9H15O6P•HCl
Molmasse
286.65
Löslichkeit
Miscible with water and methanol.

Anwendungen

Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

Bemerkungen

Air sensitive. Store in cool place. Incompatible with strong oxidizing agents

Literaturverweise

La, M.; Feng, Y.; Yang, C.; Chen, C. Performances of p-Aminophenol Redox Cycling by Thiols and Tris (2-carboxyethyl) phosphine on Cysteamine-and 3-Mercaptopropionic acid-Covered Gold Electrodes. Int. J. Electrochem. Sci. 2014, 9, 6985-6992.

Miralles, G.; Verdie?, P.; Puget, K.; Maurras, A.; Martinez, J.; Subra, G. Microwave-mediated reduction of disulfide bridges with supported (Tris (2-carboxyethyl) phosphine) as resin-bound reducing agent. ACS Comb. Sci. 2013, 15 (4), 169-173.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
8
Verpackungsgruppe
III
Harmonized Tariff Code
2931.39
TSCA
No

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