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116574-71-1 - (±)-1-Boc-3-(hydroxymethyl)piperidine, 97% - 1-Boc-3-piperidinemethanol - H52784 - Alfa Aesar

H52784 (±)-1-Boc-3-(hydroxymethyl)piperidine, 97%

CAS-Nummer
116574-71-1
Synonyme
1-Boc-3-piperidinemethanol

Größe Preis ($) Menge Verfügbarkeit
5g 83,40
25g 330,00
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(±)-1-Boc-3-(hydroxymethyl)piperidine, 97%

MDL
MFCD03094733

Chemische Eigenschaften

Formel
C11H21NO3
Molmasse
215.29
Schmelzpunkt
77-81°
Löslichkeit
Soluble in methanol and dimethylformamide(DMF).

Anwendungen

(+/-)-1-Boc-3-(hydroxymethyl)piperidine is used as a reactant for synthesis of Pim-1 inhibitors, Vasopressin1b receptor antagonists, CXCR4 antagonists as anti-HIV agents, Amide CCR5 antagonist, PSSRI-based inhibitors of S. aureus multidrug efflux pumps and Human GnRH receptor antagonists.

Bemerkungen

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literaturverweise

Peter Beak; Won Koo Lee. .alpha.-Lithioamine synthetic equivalents: syntheses of diastereoisomers from Boc derivatives of cyclic amines. J. Org. Chem. 1993, 58, (5),1109-1117

 

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2933.39
TSCA
No

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