N,N'-Di-Boc-1H-pyrazole-1-carboxamidine is used in the stereoselective synthesis of the bicyclic guanidine alkaloid (+)-monanchorin.
Gregory J. Gabriel.; Ahmad E. Madkour.; Jeffrey M. Dabkowski.; Christopher F. Nelson.; Klaus Nüsslein.; Gregory N. Tew. Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties.Biomacromolecules. 2008, 9 (11),2980-2983.
Luca Gentilucci.; Giuliana Cardillo.; Federico Squassabia.; Alessandra Tolomelli.; Santi Spampinato.; Antonino Sparta.; Monica Baiula. Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. Bioorg. Med. Chem. Lett. 2007, 17 (8),2329-2333.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.