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1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfuric acid proteins. is a versatile reagent for synthesis of perhydroazulenes, prostaglandin products (biologically active unsaturated 20-carbon fatty acids including a 5-carbon ring, derived enzymatically ), and Knoevenagel products.
Amos B. SmithIII.; Bruce D. Dorsey.; Masashi Ohba.; Andrew T. LupoJr.; Michael S. Malamas. Preparation, reactivity, and spectral properties of 1,3-dioxin vinylogous esters: versatile .beta.-ketovinyl cation equivalents. J. Org. Chem. 1988, 53 (18),4314-4325.
Hideaki Watanabe , Mitsuhiro Iwamoto.; Masahisa Nakada. Preparation of New Chiral Building Blocks:? Highly Enantioselective Reduction of Prochiral 1,3-Cycloalkanediones Possessing a Methyl Group and a Protected Hydroxymethyl Group at Their C2 Position with Baker's Yeast or CBS Catalyst.J. Org. Chem. 2005, 70 (12),4652-4658.