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7355-55-7 - 7-Deazaguanine, 97% - 2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine - H54595 - Alfa Aesar

H54595 7-Deazaguanine, 97%

CAS-Nummer
7355-55-7
Synonyme
2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine

Größe Preis ($) Menge Verfügbarkeit
250mg 246,57
1g 1293,00
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7-Deazaguanine, 97%

MDL
MFCD00079103

Chemische Eigenschaften

Formel
C6H6N4O
Molmasse
150.14
Löslichkeit
Soluble in N,N-Dimethylformamide, Dimethyl sulfoxide.

Anwendungen

Ethidium bromide efficiently intercalates into synthetic duplex DNAs with 7-deazaguanine in place of guanine, but shows none of the fluorescence enhancement usually observed upon intercalation. 7-Deazaadenine-duplexes show about 70% of the expected fluorescence enhancement.

Bemerkungen

Store at room temperature. Keep away from oxidizing agents and acids.

Literaturverweise

L J Latimer.; J S Lee. Ethidium bromide does not fluoresce when intercalated adjacent to 7-deazaguanine in duplex DNA. The Journal of Biological Chemistry. 1991, 26613849-13851..

Nabih S. Girgis.; Maged A. Michael.; Donald F. Smee.; Hassan A. Alaghamandan.; Roland K. Robins.; Howard B. Cottam. Direct C-glycosylation of guanine analogs: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides.J. Med. Chem. 1990, 33 (11),2750-2755.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
512680
Harmonized Tariff Code
2933.59
TSCA
No

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