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Indole-2-carboxaldehyde is a useful starter in indole and natural product chemistry.
Michael D. Meyer.; Lawrence I. Kruse. Ergoline synthons: Synthesis of 3,4-dihydro-6-methoxybenz[cd]indol-5(1H)-one (6-methoxy-Uhle's ketone) and 3,4-dihydrobenz[cd]indol-5(1H)-one (Uhle's ketone) via a novel decarboxylation of indole-2-carboxylates. J. Org. Chem. 1984, 49 (17),3195-3199.
Subhasish Biswas.; Virender Singh.; Sanjay Batra. Morita-Baylis-Hillman reaction of indole-2-carboxaldehyde: new vistas for indole-annulated systems. Tetrahedron. 2010, 66 (39),7781-7786.
Gefahrenhinweise (EU): H319
Causes serious eye irritation.
Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.