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7-Bromo-1-heptanol was used in the synthesis of (9Z,12E)-[1-13C]-octadeca-9,12-dienoic acid and(9Z,12Z,15E)-[1-13C]-octadeca-9,12,15-trienoic acid. It can be used to prepare N-substituted [(carboxymethyl)phenoxy]ethyl benzoxazinones as PPARγ agonists and antidiabetic (type 2) agents. It can also be used to prepare thiochroman and chroman derivatives as pure antiestrogens.
O.Loreau; A.Maret; D.Poullain; J.M.Chardigny; J.L.Sebedio; B.Beaufrere; J.P.Noel. Large-scale preparation of (9Z,12E)-[1-(13)C]-octadeca-9,12-dienoic acid, (9Z,12Z,15E)-[1-(13)C]-octadeca-9,12,15-trienoic acid and their [1-(13)C] all-cis isomers. Chemistry and Physics of Lipids. 2000, 106,(1), 65-78.
Shigefumi Kuwahara; Etsuko Morihiro; Akira Nemoto; Akira Hiramatsu. Synthesis and absolute configuration of a cytotoxic fatty acid isolated from the mushroom, Hericium erinaceum. Bioscience, Biotechnology, and Biochemistry. 1992, 56,(9), 1417-1419.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.