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1780-31-0 - 2,4-Dichloro-5-methylpyrimidine, 98% - H55206 - Alfa Aesar

H55206 2,4-Dichloro-5-methylpyrimidine, 98%

CAS-Nummer
1780-31-0
Synonyme

Größe Preis ($) Menge Verfügbarkeit
250mg 15,20
1g 44,00
5g 162,00
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2,4-Dichloro-5-methylpyrimidine, 98%

MDL
MFCD00023197
EINECS
217-227-8

Chemische Eigenschaften

Formel
C5H4Cl2N2
Molmasse
163.01
Schmelzpunkt
26-28°
Siedepunkt
108-109°/11mm
Flammpunkt
113°(235°F)
Dichte
1.39
Löslichkeit
Soluble in chloroform, ether, ethyl acetate and toluene

Anwendungen

2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

Bemerkungen

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Henry C. Koppel.; Robert Henre Springer.; Roland K. Robins.; C. C. Cheng. Pyrimidines. V. Analogs of 2-(o-Chlorobenzylthio)-4-dimethylamino- 5-methylpyrimidine (Bayer DG-428)1. J. Org. Chem. 1962, 27, 91), 181-185.

Bryan W. Roberts.; Joseph B. Lambert.; John D. Roberts. Nitrogen-15 Magnetic Resonance Spectroscopy. VI. Pyrimidine Derivatives1,2. J. Am. Chem. Soc. 1965, 87, (23), 5439-5441.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
8
Verpackungsgruppe
II
Harmonized Tariff Code
2933.59
TSCA
Yes

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