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220290-68-6 - 2-Oxa-6-azaspiro[3.4]octane, 95% - H57579 - Alfa Aesar

H57579 2-Oxa-6-azaspiro[3.4]octane, 95%

CAS-Nummer
220290-68-6
Synonyme

Größe Preis ($) Menge Verfügbarkeit
250mg 343,00
500mg 571,00
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2-Oxa-6-azaspiro[3.4]octane, 95%

MDL
MFCD14586455

Chemische Eigenschaften

Formel
C6H11NO
Molmasse
113.16
Siedepunkt
187°
Flammpunkt
63°(145°F)
Dichte
1.08
Löslichkeit
Soluble in water.

Anwendungen

2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.

Bemerkungen

Incompatible with strong oxidizing agents, strong acids, reducing agents and bases.

Literaturverweise

Zhao, F.; Lin, Z.; Wang, F.; Zhao, W.; Dong, X. Four-membered heterocycles-containing 4-anilino-quinazoline derivatives as epidermal growth factor receptor (EGFR) kinase inhibitors. Bioorg. Med. Chem. Lett. 2013, 23 (19), 5385-5388.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Sicherheitshinweise: P210-P261-P280-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2934.99
TSCA
No

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