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5399-87-1 - 6-Chloropurine riboside, 98% - 6-Chloropurine-9-beta-D-ribofuranoside - 6-Chloro-9-(beta-D-ribofuranosyl)purine - H59634 - Alfa Aesar

H59634 6-Chloropurine riboside, 98%

CAS-Nummer
5399-87-1
Synonyme
6-Chloropurine-9-beta-D-ribofuranoside
6-Chloro-9-(beta-D-ribofuranosyl)purine

Größe Preis ($) Menge Verfügbarkeit
1g 99,00
5g 346,00
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6-Chloropurine riboside, 98%

MDL
MFCD00005738
EINECS
226-438-4

Chemische Eigenschaften

Formel
C10H11ClN4O4
Molmasse
286.67
Schmelzpunkt
158-162° dec.
Löslichkeit
Soluble in water. (10.6 mg/mL)

Anwendungen

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Bemerkungen

Keep away from heat and humidity. Incompatible with strong oxidizing agents.

Literaturverweise

Juli Alonso.; M.Victòria Nogués.; Claudi M. Cuchillo. Modification of bovine pancreatic ribonuclease A with 6-chloropurine riboside. Arch. Biochem. Biophys. 1986, 246 (2),681-689.

Michal Hocek .; Antonín Holý.; Ivan Votruba.; Hana Dvo?áková. Synthesis and Cytostatic Activity of Substituted 6-Phenylpurine Bases and Nucleosides:? Application of the Suzuki-Miyaura Cross-Coupling Reactions of 6-Chloropurine Derivatives with Phenylboronic Acids.J. Med. Chem. 2000, 43 (9),1817-1825.

Weitere Referenzen

Beilstein
40573
Harmonized Tariff Code
2934.99
TSCA
No

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Kürzlich angesehen

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