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1,4-Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii is known to promote the proliferation of Bifidobacterium. It has potential therapeutic application for psoriasis treatment.
Yoshikiyo Okada; Yoshikazu Tsuzuki; Kazuyuki Narimatsu; Hirokazu Sato; Toshihide Ueda; Hideaki Hozumi; Shingo Sato; Ryota Hokari; Chie Kurihara; Shunsuke Komoto; Chikako Watanabe; Kengo Tomita; Atsushi Kawaguchi; Shigeaki Nagao; Soichiro Miura. 1,4-Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii reduces inflammation in interleukin-10-deficient mice with colitis by suppressing macrophage-derived proinflammatory cytokines. Journal of Leukocyte Biology. 2013, 94,(3), 473-480.
Chong-Fai Mok; Chuan-Ming Xie; Kathy Wai-Yan Sham; Zhi-Xiu Lin; Christopher Hon-Ki Cheng. 1,4-dihydroxy-2-naphthoic acid induces apoptosis in human keratinocyte: Potential application for psoriasis treatment. Evidence-based Complementary and Alternative Medicine. 2013, 2013,792840.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.