Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

112529-15-4 - Pioglitazone hydrochloride, 98% - 5-(4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl)thiazolidine-2,4-dione hydrochloride - H60507 - Alfa Aesar

H60507 Pioglitazone hydrochloride, 98%

CAS-Nummer
112529-15-4
Synonyme
5-(4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl)thiazolidine-2,4-dione hydrochloride

Größe Preis ($) Menge Verfügbarkeit
250mg 40,17
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Pioglitazone hydrochloride, 98%

MDL
MFCD04975446

Chemische Eigenschaften

Formel
C19H20N2O3S•HCl
Molmasse
392.90
Löslichkeit
Soluble in water (<1 mg/ml at 25°C), DMF, methanol, ethanol (4 mg/ml at 25°C), and DMSO (79 mg/ml at 25°C).

Anwendungen

Pioglitazone hydrochloride exhibits antiinflammatory and antiarteriosclerotic effects. It is used to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-&#945; mRNA produced by aspirin-induced gastric mucosal injury. Pioglitazone Hydrochloride is an activator of PPAR &#947;. It is a PPAR&#947; agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor &#947; (PPAR-&#947;) and to a lesser extent PPAR-&#945;.

Bemerkungen

Store in a cool, dry conditions in a well sealed container. Store away from oxidizing agents.

Literaturverweise

S Kersten; B Desvergne; W Wahli. Roles of PPARs in health and disease. Nature.2000, 405 (6785), 421-424.

Klemens Budde; Hans-Hellmut Neumayer; Lutz Fritsche; Wladyslaw Sulowicz; Tomasz Stompôr; David Eckland. The pharmacokinetics of pioglitazone in patients with impaired renal function. British Journal of Clinical Pharmacology.2003, 55 (4), 368-374.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H319

Causes serious eye irritation.

Sicherheitshinweise: P280-P264-P305+P351+P338-P337+P313

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.

Weitere Referenzen

Harmonized Tariff Code
2934.10
TSCA
No
RTECS
XJ5813440

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf