5-Chlorothiophene-2-carbonyl chloride used as a intermediate for rivaroxaban.
Uroš Trstenjak; Janez Ilaš; and Danijel Kikelj. Spoerri. Transformation of a selective factor Xa inhibitor rivaroxaban into a dual factor Xa/thrombin inhibitor by modification of the morpholin-3-one moiety. Med. Chem. Commun. 2014, 5197-202.
Li, Chao; Liu, Yingshuai; Zhang, Yongjun; Zhang, Xingxian. Spoerri. An approach to the anticoagulant agent rivaroxaban via an isocyanate-oxirane cycloaddition promoted by MgI2.etherate. Journal of Chemical Research. 2011, 35400-401(2).
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.