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52-24-4 - Tri(1-aziridinyl)phosphine sulfide, 98% - Triethylenethiophosphoramide - Thio-TEPA - H61778 - Alfa Aesar

H61778 Tri(1-aziridinyl)phosphine sulfide, 98%

CAS-Nummer
52-24-4
Synonyme
Triethylenethiophosphoramide
Thio-TEPA

Größe Preis ($) Menge Verfügbarkeit
1g 102,00
5g 470,00
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Tri(1-aziridinyl)phosphine sulfide, 98%

MDL
MFCD00145452
EINECS
200-135-7

Chemische Eigenschaften

Formel
C6H12N3PS
Molmasse
189.22
Löslichkeit
Soluble in benzene, acetone and methanol.

Anwendungen

Tri(1-aziridinyl)phosphine sulfide is useful for the treatment of cancers, especially cancers resistant to chemotherapy. Antineoplastic. Thio-TEPA (N,N’N’-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and bladder cancer. It is also used as conditioning treatment prior to hematopoietic progenitor cell transplantation (HPCT)

Bemerkungen

Store in cool, well ventilated area. Keep container tightly closed. Store away from oxidizing agent.

Literaturverweise

Craig Knox et. al. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Research. 2011, 39(3), D1035-D1041.

A J Wyrobek; and W R Bruce. Chemical induction of sperm abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. 1975, 72(11), 4425-4429.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H340-H350

Fatal if swallowed. May cause genetic defects. May cause cancer.

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
6.1
Verpackungsgruppe
I
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
SZ2975000

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