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239074-29-4 - trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane, 97% - tert-Butyl trans-(4-hydroxymethyl)cyclohexylcarbamate - trans-4-(Boc-amino)cyclohexanemethanol - H62487 - Alfa Aesar

H62487 trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane, 97%

CAS-Nummer
239074-29-4
Synonyme
tert-Butyl trans-(4-hydroxymethyl)cyclohexylcarbamate
trans-4-(Boc-amino)cyclohexanemethanol

Größe Preis ($) Menge Verfügbarkeit
1g 65,30
5g 245,00
25g 979,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane, 97%

MDL
MFCD03844605

Chemische Eigenschaften

Formel
C12H23NO3
Molmasse
229.31
Löslichkeit
Slightly Soluble (4.4 g/L) (25°C).

Anwendungen

trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane is used to prepare C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors. It is also used to prepare Mer kinase inhibitors for treatment of pediatric acute lymphoblastic leukemia.

Bemerkungen

Store in cool, dry place in tightly closed container. Keep container tightly closed. Store away from oxidizing agent.

Literaturverweise

Liu, J., et al. Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia. ACS Med Chem Lett. 2012, 3(2), 129-134.

Zak, M., et al. Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2. J. Med. Chem. 2013, 56(11), 764-4785.

Weitere Referenzen

Harmonized Tariff Code
2924.29
TSCA
No

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