2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Damien Y. Duveau; Adam Yasgar; Yuhong Wang; Xin Hu; Jennifer Kouznetsova; Kyle R. Brimacombe; Ajit Jadhav; Anton Simeono; Craig J. Thomas; David J. Maloneyl. Structure-activity relationship studies and biological characterization of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2014, 24 (2), 401-409.
H- H. Tai; H. Cho, M. Tong; and Y. Ding. NAD+-Linked 15-Hydroxyprostaglandin Dehydrogenase: Structure and Biological Functions. Curr. Pharm. Des. 2006, 12 (8), 955 - 962.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.