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64622-16-8 - 2-Bromo-6-chlorobenzaldehyde, 98% - H64605 - Alfa Aesar

H64605 2-Bromo-6-chlorobenzaldehyde, 98%

CAS-Nummer
64622-16-8
Synonyme

Größe Preis ($) Menge Verfügbarkeit
250mg 40,79
1g 109,18
5g 407,88
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2-Bromo-6-chlorobenzaldehyde, 98%

MDL
MFCD00266792

Chemische Eigenschaften

Formel
C7H4BrClO
Molmasse
219.46
Schmelzpunkt
81-86°
Löslichkeit
Slightly soluble in water. 

Anwendungen

2-Bromo-6-chlorobenzaldehyde plays an important role as a linker, which provides higher selectivity and reactivity in the Buchwald C-N bond forming reaction in order to prepare Bruton's tyrosine kinase inhibitor.

Bemerkungen

Store in a cool place. Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literaturverweise

Sahn, J. J.; Su, J. Y.; Martin, S. F. Facile and unified approach to skeletally diverse, privileged scaffolds. 2011, 13 (10), 2590-2593.

Donald, J. R.; Granger, B. A.; Hardy, S.; Sahn, J. J.; Martin, S. F. Applications of Multicomponent Assembly Processes To the Facial Synthesis of Diversely Functionalized Nitrogen Heterocycles. 2012, 84 (2), 1089.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
2613087
Harmonized Tariff Code
2913.00
TSCA
No

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