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2075-45-8 - 4-Bromo-1H-pyrazole, 98+% - H64673 - Alfa Aesar

H64673 4-Bromo-1H-pyrazole, 98+%

CAS-Nummer
2075-45-8
Synonyme

Größe Preis ($) Menge Verfügbarkeit
25g 31,80
500g 269,00
1kg 449,00
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4-Bromo-1H-pyrazole, 98+%

MDL
MFCD00075602

Chemische Eigenschaften

Formel
C3H3BrN2
Molmasse
146.97
Schmelzpunkt
93-96° lit.
Siedepunkt
250-260° lit.
Löslichkeit
Slightly soluble in water.

Anwendungen

4-Bromopyrazole may be used in the preparation of 4-bromo-1-(2-chloroethyl)-1H-pyrazole. It may be used as starting material in the synthesis of 1,4?-bipyrazoles. Also used in the synthesis of various pharmaceutical and biologically active compounds, including inhibitors. It is also shown to be one of the 4-substituted pyrazoles, being able to act as inhibitor of liver alcohol dehydrogenase.

Bemerkungen

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literaturverweise

Guzei IA; and Winter CH. Structural Diversity in the Reaction of Mono- and Disubstituted Pyrazoles with Titanium Tetrachloride. Importance of Hydrogen Bonding and Trends in cis/trans Geometry of Binary Adducts with Unidentate Ligands. Inorg. Chem. 1997 36(20), 4415-4420.

E Alejandre-Durán; M Ruiz-Rubio; R M Claramunt; C López; C Pueyo. Mutagenicity study on pyrazole, seven pyrazole derivatives, and two nitroimidazoles with the L-arabinose resistance test of Salmonella typhimurium. Environmental Mutagenesis.1986 8(4), 611-619.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
106510
Harmonized Tariff Code
2933.19
TSCA
No
RTECS
UQ6200000

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