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486424-37-7 - 3-Amino-6-bromopyrazine-2-carboxylic acid, 98% - H66908 - Alfa Aesar

H66908 3-Amino-6-bromopyrazine-2-carboxylic acid, 98%

CAS-Nummer
486424-37-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 24,49
5g 122,43
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3-Amino-6-bromopyrazine-2-carboxylic acid, 98%

MDL
MFCD08275681

Chemische Eigenschaften

Formel
C5H4BrN3O2
Molmasse
218.01
Schmelzpunkt
178-183°
Sensitivität
Light Sensitive
Löslichkeit
Soluble in dimethyl sulfoxide and methanol.

Anwendungen

3-Amino-6-bromopyrazine-2-carboxylic acid used to prepare 3-bromo-5-phenylpyrazine-2-amine. It serves as an intermediate in organic synthesis and pharmaceuticals.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Woodland, A.; Thompson, S.; Cleghorn, L. A. T.; Norcross, N.; De Rycker, M.; Grimaldi, R.; Hallyburton, I.; Rao, B.; Norval, S.; Stojanovski, L.; Brun, R.; Kaiser, M.; Frearson, J. A.; Gray1, D. W.; Wyatt, P. G.; Read, K. D.; Gilbert, I. H. Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library. ChemMedChem 2015, 10 (11), 1809-1820.

Thompson, A. E.; Batsanov, A. S.; Bryce, M. R.; Saygili, N.; Parry, P. R.; Tarbit, B. 2-Ethoxy-3-pyridylboronic acid: a versatile reagent for the synthesis of highly-functionalised 3-aryl/heteroaryl-pyridines via Suzuki cross-coupling reactions. Tetrahedron 2005, 61 (21), 5131-5135.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
147851
Harmonized Tariff Code
2933.39
TSCA
No

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