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3-Amino-6-bromopyrazine-2-carboxylic acid used to prepare 3-bromo-5-phenylpyrazine-2-amine. It serves as an intermediate in organic synthesis and pharmaceuticals.
Woodland, A.; Thompson, S.; Cleghorn, L. A. T.; Norcross, N.; De Rycker, M.; Grimaldi, R.; Hallyburton, I.; Rao, B.; Norval, S.; Stojanovski, L.; Brun, R.; Kaiser, M.; Frearson, J. A.; Gray1, D. W.; Wyatt, P. G.; Read, K. D.; Gilbert, I. H. Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library. ChemMedChem 2015, 10 (11), 1809-1820.
Thompson, A. E.; Batsanov, A. S.; Bryce, M. R.; Saygili, N.; Parry, P. R.; Tarbit, B. 2-Ethoxy-3-pyridylboronic acid: a versatile reagent for the synthesis of highly-functionalised 3-aryl/heteroaryl-pyridines via Suzuki cross-coupling reactions. Tetrahedron 2005, 61 (21), 5131-5135.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.