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Spironolactone used as potassium sparing diuretic. Also used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome.
Jakob Nielsen et. al. Sodium transporter abundance profiling in kidney: effect of spironolactone. American Journal of Physiology - Renal Physiology, 2002, 283(5), F923-F933.
Femke Waanders et. al. Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats. American Journal of Physiology - Renal Physiology, 2009,296,(5), F1072-F1079.
Gefahrenhinweise (EU): H302-H360
Harmful if swallowed. May damage fertility or the unborn child.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.