I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
2-Iminothiolane hydrochloride is predominantly used as an amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides. It is also used as a RNA-protein crosslinking reagent as well as useful in cross-linking proteins..
A Bernkop-Schnürch.; M Hornof.; T Zoidl. Thiolated polymersthiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates. International Journal of Pharmaceutics. 2003, 260,(2), 229-237.
R Jue.; JM Lambert.; LR Pierce.; RR Traut. Addition of sulfhydryl groups of Escherichia coli ribosomes by protein modification with 2-iminothiolane (methyl 4-mercaptobutyrimidate). Biochemistry. 1978, 17,(25), 5399-5406.