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159351-69-6 - Everolimus - J60139 - Alfa Aesar

J60139 Everolimus

CAS-Nummer
159351-69-6
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5mg 139,00
10mg 205,00
25mg 352,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Everolimus

MDL
MFCD07785165

Chemische Eigenschaften

Formel
C53H83NO14
Molmasse
958.22
Form
Powder
Löslichkeit
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.

Anwendungen

Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Puricel, S.; Arroyo, D.; Corpataux N.; Baeriswyl, G.; Lehmann, N.; Kallinikou, Z.; Muller, O.; Allard, L.; Stauffer, J.; Togni, M.; Goy, J.; Cook, S. Comparison of Everolimus- and Biolimus-Eluting Coronary Stents With Everolimus-Eluting Bioresorbable Vascular Scaffolds. J. Am. Coll. Cardiol. 2015, 65 (8), 791-801.

Naruse, T.; Yanamoto, S.; Yamada, S.; Rokutanda, S.; Kawakita, A.; Kawasaki, G.; Umeda, M. Anti-Tumor Effect of the Mammalian Target of Rapamycin Inhibitor Everolimus in Oral Squamous Cell Carcinoma. Pathol. Oncol. Res. 2015, 21 (3), 765-773.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H372

Causes damage to organs through prolonged or repeated exposure.

Sicherheitshinweise: P260-P264-P270-P314-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Get medical advice/attention if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3907
Harmonized Tariff Code
2934.99
TSCA
No

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