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Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC.
Puricel, S.; Arroyo, D.; Corpataux N.; Baeriswyl, G.; Lehmann, N.; Kallinikou, Z.; Muller, O.; Allard, L.; Stauffer, J.; Togni, M.; Goy, J.; Cook, S. Comparison of Everolimus- and Biolimus-Eluting Coronary Stents With Everolimus-Eluting Bioresorbable Vascular Scaffolds. J. Am. Coll. Cardiol. 2015, 65 (8), 791-801.
Naruse, T.; Yanamoto, S.; Yamada, S.; Rokutanda, S.; Kawakita, A.; Kawasaki, G.; Umeda, M. Anti-Tumor Effect of the Mammalian Target of Rapamycin Inhibitor Everolimus in Oral Squamous Cell Carcinoma. Pathol. Oncol. Res. 2015, 21 (3), 765-773.
Gefahrenhinweise (EU): H372
Causes damage to organs through prolonged or repeated exposure.
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