Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

65-19-0 - Yohimbine hydrochloride, 98+% - 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride - J60185 - Alfa Aesar

J60185 Yohimbine hydrochloride, 98+%

CAS-Nummer
65-19-0
Synonyme
17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride

Yohimbine hydrochloride, 98+%

MDL
MFCD00012674
EINECS
200-600-4

Chemische Eigenschaften

Formel
C21H26N2O3•HCl
Molmasse
390.91
Form
Powder
Schmelzpunkt
288-290°
Sensitivität
Light Sensitive
Löslichkeit
Soluble in dimethyl sulfoxide and methanol.

Anwendungen

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. It blocks the central α2-adrenegic receptors in the brain, thus preventing and reducing the effects of xylazine, an α2-adrenergic agonist. The sedative effects and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect, and increases heart rate and blood pressure.

Bemerkungen

Light Sensitive, store in dark. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literaturverweise

W Zhang and G M Roomans. A yohimbine-dependent, UK14,304 induced ion transient in HT29 cells studied by X-ray microanalysis. Scanning microscopy, 1996, 10(1), 293-299.

Susan X. Jiang et. al. Reversible inhibition of intracellular calcium influx through NMDA receptors by imidazoline I2receptor antagonists. European Journal of Pharmacology, 2010,629,(1), 12-19.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H310-H330

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.

Sicherheitshinweise: P301+P310a-P304+P340-P320-P330-P405-P501a

IF SWALLOWED: Immediately call a POISON CENTER/doctor IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,10102
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2939.80
TSCA
Yes
RTECS
ZG1015000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf