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Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.
T Hayashi, I Suenaga; N Narukawa; T Yamazaki. In vitro and in vivo activities of sedecamycin against Treponema hyodysenteriae. Antimicrobial Agents and Chemotherapy. 1988, 32 (4), 458-461.
Torey Looft; Heather K Allen; Thomas A Casey; David P Alt; Thaddeus B Stanton. Carbadox has both temporary and lasting effects on the swine gut microbiota. Dyes and Pigments. 2014, 5, 276.
Gefahrenhinweise (EU): H228-H302-H350
Flammable solid. Harmful if swallowed. May cause cancer.
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.