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10592-13-9 - Doxycycline hydrochloride - J60422 - Alfa Aesar

J60422 Doxycycline hydrochloride

CAS-Nummer
10592-13-9
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 42,50
5g 74,57
25g 297,67
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Doxycycline hydrochloride

MDL
MFCD03427564
EINECS
234-198-7

Chemische Eigenschaften

Formel
C22H24N2O8•HCl
Molmasse
480.90
Form
Crystalline powder
Schmelzpunkt
195-201°
Löslichkeit
Soluble in water to 50mg/ml. May require warming.

Anwendungen

Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinases.Doxycycline hydrochloride is an antibiotic used to inhibit matrix metalloproteinases like type 1 collagenase in studies on would healing and tissue remodeling. It shows the broad spectrum antibacterial and antiprotozoan activity. It is often used to treat lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax.

Bemerkungen

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.

Literaturverweise

Gad, H. A.; Kamel, A. O.; Sammour, O. A.; Dessouky, H. F. E. Vesicular powder as carrier for doxycycline hydrochloride and metronidazole combination therapy. Pharm. Dev. Technol. 2014, 19 (6), 755-768.

Yang, S.; Li, K. Dissolution profile study on the novel doxycycline hydrochloride sustained-release capsules. Pak. J. Pharm. Sci. 2014, 27 (5), 1615-1620.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2941.30
TSCA
No

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Metalle und Stoffe

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