Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

75567-37-2 - Ingenol 3-angelate, 98% - J60601 - Alfa Aesar

J60601 Ingenol 3-angelate, 98%

CAS-Nummer
75567-37-2
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1mg 194,25
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Ingenol 3-angelate, 98%

MDL
MFCD07784504

Chemische Eigenschaften

Formel
C25H34O6
Molmasse
348.40
Form
Powder
Löslichkeit
Soluble in 100% ethanol, DMSO, dichloromethane, and methanol. Insoluble in water.

Anwendungen

Ingenol 3-Angelate is used as a PKC activator, anticancer, and immunostimulant compound. It is also used to exhibits antileukemic activity, induces nuclear translocation of PKCδ, and induces apoptosis in acute myeloid leukemia (AML) cell lines and primary AML blast cells. Also displays antiproliferative effects and induces apoptosis in Colo205 cells.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C

Literaturverweise

Kedei et al. Characterization of the interaction of ingenol-3-angelate with protein kinase C. Cancer Res. 2004, 64, (9), 3243-55.

Hampson et al. PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC. Blood . 2005, 106, (4), 1362-8.

Weitere Referenzen

Harmonized Tariff Code
2916.19
TSCA
No

Empfohlen

  • A16986

    beta-Bromostyrene, cis + trans, 96%, stab. with 0.1% 4-tert-butylcatechol
  • A18812

    Nerolidol, cis + trans, 97+%
  • H64740

    4-(4-Chlorobenzoyl)piperidine, 97%
  • H63555

    1-Ethyl-4-(4-nitrophenyl)piperazine, 97%
  • 35576

    Ammonium hydroxide, 0.1N Standardized Solution

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf