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Aminophylline exhibits vasodilatory and anti-inflammatory activity and is occasionally clinically used to treat chronic obstructive pulmonary disorder (COPD). In animal models of allergen-induced lung inflammation, aminophylline decreases levels of IL-5, IL-8, and eosinophils. It is mostly used to prepare solutions for intravenous injections.
L Hendele.; M Weinberger. Disposition of Theophylline after a Single Intravenous Infusion of Aminophylline 1-4. American Review of Respiratory Disease. 1978, 118,(1), 97-103.
JA Elias.; AI Levinson. Hypersensitivity Reactions to Ethylenediamine In Aminophylline 1-3. American Review of Respiratory Disease. 1981, 123,(5), 550-552.
Gefahrenhinweise (EU): H301
Toxic if swallowed.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.