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961-07-9 - 2'-Deoxyguanosine - J60741 - Alfa Aesar

J60741 2'-Deoxyguanosine

CAS-Nummer
961-07-9
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 63,60
5g 128,00
10g 230,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

2'-Deoxyguanosine

MDL
MFCD00080300
EINECS
213-505-8

Chemische Eigenschaften

Formel
C10H13N5O4
Molmasse
267.25
Form
Crystalline powder
Löslichkeit
Soluble in NH4OH 1 M: 50 mg/mL, clear to very faintly turbid.

Anwendungen

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

Kasper Broedbaek et. al. Urinary 8-oxo-7,8-dihydro-2?-deoxyguanosine as a biomarker in type 2 diabetes. Free Radical Biology and Medicine. 2011, 51 (8), 1473-1479.

Aaron M Fleming et. al. Copper/H2O2-mediated oxidation of 2'-deoxyguanosine in the presence of 2-naphthol leads to the formation of two distinct isomeric adducts.. Journal of Organic Chemistry. 2011, 76 (19), 7953-7963.

Weitere Referenzen

Harmonized Tariff Code
2934.99
TSCA
Yes

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