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124182-57-6 - CGS 21680 hydrochloride, 99% - J60793 - Alfa Aesar

J60793 CGS 21680 hydrochloride, 99%

CAS-Nummer
124182-57-6
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5mg 209,00
10mg 330,00
50mg 1431,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

CGS 21680 hydrochloride, 99%

MDL
MFCD11045878

Chemische Eigenschaften

Formel
C23H29N7O6•HCl
Molmasse
535.98
Form
Solid
Löslichkeit
Soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin.

Anwendungen

CGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

Cheng, M.K.,; Doumad, A.B., Jiang, H., et al. . Epoxyeicosatrienoic acids mediate adenosine-induced vasodilation in rat prelomerular microvessels (PGMV) via A2A receptors. . Br J Pharmacol . 2004, 141 441-448 .

Phillis,J.W.. The selective adenosine A2 receptor agonist, CGS 21680, is a potent depressant of cerebral cortical neuronal activity.. Brain Res.. 1990 , 509 328-330.

Weitere Referenzen

Harmonized Tariff Code
2934.99
TSCA
No

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Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf