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39562-70-4 - Nitrendipine - J60841 - Alfa Aesar

J60841 Nitrendipine

CAS-Nummer
39562-70-4
Synonyme

Größe Preis ($) Menge Verfügbarkeit
100mg 163,00
500mg 325,00
1g 532,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Nitrendipine

MDL
MFCD00082255
EINECS
254-513-1

Chemische Eigenschaften

Formel
C18H20N2O6
Molmasse
360.36
Form
Powder
Löslichkeit
Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.

Anwendungen

Nitrendipine modulates NMDA receptor channel function in mammalian neurons. Nitrendipine has been shown to inhibit neutrophil adhesion to vascular endothelium. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

X Chen et. al.Quantitative determination of nitrendipine and its metabolite dehydronitrendipine in human plasma using liquid chromatography-tandem mass spectrometry.. Biomedical Chromatography. 2001, 15 (8), 518-524 .

J Muntwyler and F Follath.Calcium channel blockers in treatment of hypertension.. Progress in Cardiovascular Diseases. 2001, 44 (3), 207-216.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H312-H332

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

Sicherheitshinweise: P261-P280-P264-P270-P304+P340-P301+P312-P312-P363-P322-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific measures (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6576
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US5653000

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