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130-61-0 - Thioridazine hydrochloride - J60895 - Alfa Aesar

J60895 Thioridazine hydrochloride

CAS-Nummer
130-61-0
Synonyme

Thioridazine hydrochloride

MDL
MFCD00012655
EINECS
204-992-8

Chemische Eigenschaften

Formel
C21H26N2S2•HCl
Molmasse
407.03
Form
Powder
Schmelzpunkt
161-163°
Sensitivität
Light Sensitive & Hygroscopic
Löslichkeit
Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.

Anwendungen

Thioridazine is a piperidine typical antipsychotic drug belonging to the phenothiazine widely used in the treatment of schizophrenia and psychosis. It primary use in medicine was the treatment of schizophrenia.This medication is used to treat certain mental/mood disorders (e.g., schizophrenia). Thioridazine·HCl is a calcium channel protein inhibitor as well as a D2DR/D4DR inhibitor. It is an intercalating agent for analyzing the integrity of double stranded DNA by using the square-wave voltammetry.

Bemerkungen

Light Sensitive & Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light, water, moisture.

Literaturverweise

H. Garfield Kelly,; J. E. Fay,; S. G. Laverty.Thioridazine Hydrochloride (Mellaril): Its Effect on the Electrocardiogram and a Report of Two Fatalities with Electrocardiographic Abnormalities. Can Med Assoc J. 1963, 89 (11), 546-554.

John R. Huston, MD; George E. Bell, MD.The Effect of Thioridazine Hydrochloride and Chlorpromazine on the Electrocardiogram. JAMA. 1966, 198 (1), 16-20..

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H400-H410-H302-H315-H319-H335

Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P273-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,9359
Gefahrenklasse
9
Verpackungsgruppe
III
Harmonized Tariff Code
2934.30
TSCA
No
RTECS
SP2275000

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