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2068-78-2 - Vincristine sulfate, 98+% - J60907 - Alfa Aesar

J60907 Vincristine sulfate, 98+%

CAS-Nummer
2068-78-2
Synonyme

Größe Preis ($) Menge Verfügbarkeit
10mg 133,00
25mg 265,00
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Vincristine sulfate, 98+%

MDL
MFCD00084729
EINECS
218-190-0

Chemische Eigenschaften

Formel
C46H58N4O14S
Molmasse
923.04
Form
Powder
Schmelzpunkt
>300°
Siedepunkt
273-281°
Löslichkeit
Soluble in DMSO at 60mg/ml. Soluble in water at 25mg/ml with warming. Very poorly soluble in ethanol

Anwendungen

Vincristine sulfate, is used as an anticancer agent, microtubule disrupter, Induces apoptosis in human lymphoma cells. Other applications include as a cell cycle arresting, apoptotic inducing alkaloid.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away fom strong oxidizing agents, heavy metal salts.

Literaturverweise

Jordan et al.  Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 1985, 45  ,(6), 2741-7.

Takano et al. Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate. Pathol.Res.Pract. 1993, 189 ,(2), 197-203.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H341-H360

Fatal if swallowed. Suspected of causing genetic defects. May damage fertility or the unborn child.

Sicherheitshinweise: P201-P280-P301+P310a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,9986
Beilstein
3924631
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2939.80
TSCA
No
RTECS
OH6340000

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