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145-73-3 - Endothall - 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid - J60948 - Alfa Aesar

J60948 Endothall

CAS-Nummer
145-73-3
Synonyme
7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Größe Preis ($) Menge Verfügbarkeit
100mg 349,17
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Endothall

MDL
MFCD00137362
EINECS
205-660-5

Chemische Eigenschaften

Formel
C8H10O5
Molmasse
186.20
Form
Powder
Löslichkeit
Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.

Anwendungen

Endothall is used as an inhibitor of PP2A phosphatase activity. It is also used as a defoliant. It is used as a cell adhesion inhibitor.

Bemerkungen

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

Literaturverweise

F Erdodi.; B Toth.; K Hirano.; M Hirano. Endothall thioanhydride inhibits protein phosphatases-1 and-2A in vivo. American Journal of Physiology - Cell Physiology. 1995, 269 ,(5), C1176-C1184.

YM Li.; C Mackintosh.; JE Casida. Protein phosphatase 2A and its [3 H] cantharidin/[3 H] endothall thioanhydride binding site: Inhibitor specificity of cantharidin and ATP analogues. Biochemical pharmacology. 1993, 46 ,(8), 1435-1443.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H312-H315-H319-H335

Toxic if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3575
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2932.19
TSCA
No
RTECS
RN7875000

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