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512-04-9 - Diosgenin - 3-beta-Hydroxy-5-spirostene - Nitogenin - J60976 - Alfa Aesar

J60976 Diosgenin

CAS-Nummer
512-04-9
Synonyme
3-beta-Hydroxy-5-spirostene
Nitogenin

Größe Preis ($) Menge Verfügbarkeit
5g 34,71
25g 104,03
100g 224,80
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Diosgenin

MDL
MFCD00016887
EINECS
208-134-3

Chemische Eigenschaften

Formel
C27H42O3
Molmasse
414.63
Form
Powder
Schmelzpunkt
200-206°
Löslichkeit
Soluble in chloroform (50 mg/ml), ethanol (83 mg/ml at 25°C), water (<1 mg/ml at 25°C), DMSO (<1 mg/ml at 25°C), and methanol.

Anwendungen

Diosgenin is the precursor for the semisynthesis of progesterone which in turn was used in early combined oral contraceptive pills. The unmodified steroid has estrogenic activity and can reduce the level of serum cholesterol. Diosgenin has been used in traditional medicine as an antihypercholesterolemia, antihypertriacylglycerolemia, antidiabetes and antihyperglycemia agent. Diosgenin is a steroid sapogenin used in the semi-synthesis of pregnenolone, cortisone, and progesterone. Diosgenin has estrogenic activity and can reduce the level of serum cholesterol.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

Pin-Shern Chen,; Yuan-Wei Shih,; Hsiang-Ching Huang,; Hsing-Wen Cheng. Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression. PLoS ONE. 2011, 6 (5), e20164.

Heena J Shah,; Lele SS. Extraction of Diosgenin, a Bioactive Compound from Natural Source Dioscorea alata Var purpurae. Shah and Lele, J Anal Bioanal Techniques. 2014, 3 (4)

Weitere Referenzen

Merck
14,3295
Beilstein
94582
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
WH1450000

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