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103476-89-7 - Leupeptin hemisulfate - J61188 - Alfa Aesar

J61188 Leupeptin hemisulfate

CAS-Nummer
103476-89-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
25mg 123,00
100mg 302,00
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Leupeptin hemisulfate

MDL
MFCD00037012

Chemische Eigenschaften

Formel
C20H38N6O4•0.5H2SO4
Molmasse
475.59
Form
Powder
Löslichkeit
Soluble in water, ethanol, dimethyl formamide and acetic acid.

Anwendungen

Reversible protease inhibitor, which inhibits cathepsin B, calpain and trypsinPharmaceutical composition containing leupeptin hemisulfate is used as an anti-malarial agent. It is employed in the treatment of noise-induced hearing loss. It also protects the heart from myocardial stunning. Further, it is used to inhibit serine, cysteine proteases, plasmin, trypsin, papain, kallikrein and cathepsin B.

Bemerkungen

Store in a cool place. Incompatible with strong acids and strong bases.

Literaturverweise

Uchikawa, S.; Yoda, M.; Tohmonda, T.; Kanaji, A.; Matsumoto, M.; Toyama, Y.; Horiuchi, K. ADAM17 regulates IL-1 signaling by selectively releasing IL-1 receptor type 2 from the cell surface. Cytokine 2015, 71 (2), 238-245.

Solter, P. F.; Oyama, M. A.; Machen, M. C.; Trafny, D. J.; Sisson, D. D. Detection by ELISA of C-terminal proBNP in plasma from cats with cardiomyopathy. Vet. J. 2015, 206 (2), 213-217.

Weitere Referenzen

Harmonized Tariff Code
2925.29
TSCA
No

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