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Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.
Neelam Keswani; Sinjan Choudhary; Nand Kishore. Interaction of weakly bound antibiotics neomycin and lincomycin with bovine and human serum albumin: biophysical approach. Journal of Biochemistry. 2010, 148,(1), 71-84.
H.Malke; W.Reichardt; M.Hartmann; F.Walter. Genetic study of plasmid-associated zonal resistance to lincomycin in Streptococcus pyogenes. Antimicrobial Agents and Chemotherapy. 1981, 19,(1), 91-100.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.