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58-58-2 - Puromycin dihydrochloride, 99% - J61278 - Alfa Aesar

J61278 Puromycin dihydrochloride, 99%

CAS-Nummer
58-58-2
Synonyme

Größe Preis ($) Menge Verfügbarkeit
25mg 49,44
100mg 153,76
500mg 550,71
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Puromycin dihydrochloride, 99%

MDL
MFCD00012691
EINECS
200-387-8

Chemische Eigenschaften

Formel
C22H29N7O5•2HCl
Molmasse
544.44
Form
Powder
Schmelzpunkt
168-170°
Löslichkeit
Soluble in water

Anwendungen

It also exhibits antitumor activity in studies on brain tumor cells. Puromycin is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3¢-terminal end of aminoacyl-tRNA. It has been used to study transcriptional regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.

Bemerkungen

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literaturverweise

RA Rosson.; BM Tebo.; KH Nealson. Use of poisons in determination of microbial manganese binding rates in seawater. Appl. Environ. Microbiol. 1984, 47,(7), 740-745.

V Nair.; DJ Emanuel. Synthetic design, stereochemistry, and enzymic activity of a reversed aminoacyl nucleoside: an analog of puromycin. J. Am. Chem. Soc. 1977, 99,(5), 1571-1576.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302

Harmful if swallowed.

Sicherheitshinweise: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,7943
Beilstein
3853613
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
AU355000

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