Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

54-25-1 - 6-Azauridine - 6-Azauracil riboside - 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione - J61309 - Alfa Aesar

J61309 6-Azauridine

CAS-Nummer
54-25-1
Synonyme
6-Azauracil riboside
2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione

Größe Preis ($) Menge Verfügbarkeit
1g 80,80
5g 236,80
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

6-Azauridine

MDL
MFCD00006472
EINECS
200-199-6

Chemische Eigenschaften

Formel
C8H11N3O6
Molmasse
245.19
Form
Powder
Schmelzpunkt
160-161°
Löslichkeit
It is soluble in water.

Anwendungen

6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C

Literaturverweise

Rada B.; Dragún M. Antiviral action and selectivity of 6-azauridine. Ann N Y Acad Sci. 1977, 284, 410-7.

JM Crance.; N Scaramozzino.; A Jouan.; D Garin. Interferon, ribavirin, 6-azauridine and glycyrrhizin: antiviral compounds active against pathogenic flaviviruses. Antiviral research. 2003, 58, (1), 73-79.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H351-H302-H312-H332

Suspected of causing cancer. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

Sicherheitshinweise: P201-P261-P280-P281-P304+P340-P301+P312-P312-P363-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,904
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
XY8575000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf